Unraveling the Extraction, Structure, Bioactivities, and Structure–Activity Relationship of <i>Salvia miltiorrhiza</i> Polysaccharides: A Review

<i>Salvia miltiorrhiza</i>, a widely recognized traditional medicinal plant, is not only extensively used in clinical settings but also increasingly valued for its potential as a functional food ingredient. <i>S. miltiorrhiza</i> polysaccharides (SMPs), as the primary active components of <i>S. miltiorrhiza</i>, demonstrate excellent performance in antioxidant, hepatoprotective, and immunomodulatory effects. These attributes facilitate their advancement in nutritional health products, dietary supplements, and health-enhancing functional foods. Combining therapeutic and nutritional value, SMPs serve as a vital bridge connecting traditional medicine with modern functional food applications. This work offers a systematic assessment of the procedures for the extraction and purification of SMP, along with its structural features, biological activities, uses, and structure-activity connections. This framework is anticipated to establish a theoretical basis for subsequent research, applications, and progress in human health and product development.

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Publication Details

Journal
Journal of Agricultural and Food Chemistry
Published
2025-11-12
DOI
https://doi.org/10.1021/acs.jafc.5c10285
Primary Topic
Polysaccharides and Plant Cell Walls
Type
article
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article

Unraveling the Extraction, Structure, Bioactivities, and Structure–Activity Relationship of Salvia miltiorrhiza Polysaccharides: A Review

Shunchun Wang, Yupeng Liu, Haoran Liu, Yue Yu et al.
Journal of Agricultural and Food Chemistry
Polysaccharides and Plant Cell Walls
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Unraveling the Extraction, Structure, Bioactivities, and Structure–Activity Relationship of Salvia miltiorrhiza Polysaccharides: A Review

Shunchun Wang, Yupeng Liu, Haoran Liu, Yue Yu, Songshan Shi, Jie Chen, Feng Zhang, Huijun Wang, Yongbin Xu, Tao Pang, Paziliya Parhat
article en

Abstract

<i>Salvia miltiorrhiza</i>, a widely recognized traditional medicinal plant, is not only extensively used in clinical settings but also increasingly valued for its potential as a functional food ingredient. <i>S. miltiorrhiza</i> polysaccharides (SMPs), as the primary active components of <i>S. miltiorrhiza</i>, demonstrate excellent performance in antioxidant, hepatoprotective, and immunomodulatory effects. These attributes facilitate their advancement in nutritional health products, dietary supplements, and health-enhancing functional foods. Combining therapeutic and nutritional value, SMPs serve as a vital bridge connecting traditional medicine with modern functional food applications. This work offers a systematic assessment of the procedures for the extraction and purification of SMP, along with its structural features, biological activities, uses, and structure-activity connections. This framework is anticipated to establish a theoretical basis for subsequent research, applications, and progress in human health and product development.

Journal of Agricultural and Food ChemistryVol. 73(47)
Chinese Academy of Sciences (CN), State Administration of Traditional Chinese Medicine of the People's Republic of China (CN), Shanghai University of Traditional Chinese Medicine (CN), Shanghai Changzheng Hospital (CN), Xinjiang Technical Institute of Physics & Chemistry (CN), University of Chinese Academy of Sciences (CN)
Openalex Percentile: Top 73%
Polysaccharides and Plant Cell Walls
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