Unraveling the Extraction, Structure, Bioactivities, and Structure–Activity Relationship of <i>Salvia miltiorrhiza</i> Polysaccharides: A Review
<i>Salvia miltiorrhiza</i>, a widely recognized traditional medicinal plant, is not only extensively used in clinical settings but also increasingly valued for its potential as a functional food ingredient. <i>S. miltiorrhiza</i> polysaccharides (SMPs), as the primary active components of <i>S. miltiorrhiza</i>, demonstrate excellent performance in antioxidant, hepatoprotective, and immunomodulatory effects. These attributes facilitate their advancement in nutritional health products, dietary supplements, and health-enhancing functional foods. Combining therapeutic and nutritional value, SMPs serve as a vital bridge connecting traditional medicine with modern functional food applications. This work offers a systematic assessment of the procedures for the extraction and purification of SMP, along with its structural features, biological activities, uses, and structure-activity connections. This framework is anticipated to establish a theoretical basis for subsequent research, applications, and progress in human health and product development.
Authors
- Shunchun Wang (ORCID: https://orcid.org/0000-0003-0384-1350)
- Yupeng Liu (ORCID: https://orcid.org/0000-0003-1839-7037)
- Haoran Liu (ORCID: https://orcid.org/0000-0001-8216-3679)
- Yue Yu (ORCID: https://orcid.org/0000-0002-7473-3122)
- Songshan Shi (ORCID: https://orcid.org/0000-0002-4693-4154)
- Jie Chen (ORCID: https://orcid.org/0000-0002-7773-3160)
- Feng Zhang (ORCID: https://orcid.org/0000-0002-4954-1575)
- Huijun Wang (ORCID: https://orcid.org/0000-0001-6319-498X)
- Yongbin Xu (ORCID: https://orcid.org/0000-0003-2347-8114)
- Tao Pang (ORCID: https://orcid.org/0000-0001-5264-1051)
- Paziliya Parhat
Institutions
- Chinese Academy of Sciences (CN)
- State Administration of Traditional Chinese Medicine of the People's Republic of China (CN)
- Shanghai University of Traditional Chinese Medicine (CN)
- Shanghai Changzheng Hospital (CN)
- Xinjiang Technical Institute of Physics & Chemistry (CN)
- University of Chinese Academy of Sciences (CN)
Publication Details
- Journal
- Journal of Agricultural and Food Chemistry
- Published
- 2025-11-12
- DOI
- https://doi.org/10.1021/acs.jafc.5c10285
- Primary Topic
- Polysaccharides and Plant Cell Walls
- Type
- article
- Field-Weighted Citation Impact
- 0.00