Rethinking Gleason pattern quantification in predicting metastasis: results of 20 years of follow‐up in the Rotterdam section of the European Randomized Study of Screening for Prostate Cancer

GP3 length does not have an impact on the prediction of MFS in biopsies, once GP4/GP5 lengths are known. Although GP3 percentage is essential in Gleason grading, MFS is related to absolute GP4 and GP5 quantity rather than their proportion to GP3.

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Publication Details

Journal
Histopathology
Published
2025-11-26
DOI
https://doi.org/10.1111/his.70052
Primary Topic
Prostate Cancer Diagnosis and Treatment
Type
article
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article

Rethinking Gleason pattern quantification in predicting metastasis: results of 20 years of follow‐up in the Rotterdam section of the European Randomized Study of Screening for Prostate Cancer

Sebastiaan Remmers, Lisa J Kroon, Monique J. Roobol, L. Lucia Rijstenberg et al.
Histopathology
Prostate Cancer Diagnosis and Treatment
article

Rethinking Gleason pattern quantification in predicting metastasis: results of 20 years of follow‐up in the Rotterdam section of the European Randomized Study of Screening for Prostate Cancer

Sebastiaan Remmers, Lisa J Kroon, Monique J. Roobol, L. Lucia Rijstenberg, Charlotte F. Kweldam, Roderick C.N. van den Bergh, Ivo I. de Vos, Geert J.L.H. van Leenders
article en

Abstract

GP3 length does not have an impact on the prediction of MFS in biopsies, once GP4/GP5 lengths are known. Although GP3 percentage is essential in Gleason grading, MFS is related to absolute GP4 and GP5 quantity rather than their proportion to GP3.

HistopathologyVol. 88(4)
Maasstad Ziekenhuis (NL), Erasmus MC Cancer Institute (NL)
Openalex Percentile: Top 45%
Prostate Cancer Diagnosis and Treatment
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