Genetic Counseling in Nephrology: Challenges and Opportunities

Genetic testing is increasingly used in nephrology to diagnose hereditary kidney diseases, guide therapy, and inform transplant decisions. However, integrating genetic data into routine care presents ethical, logistical, and psychosocial challenges. This review outlines the key elements of genetic counseling in nephrology, including testing modalities, informed consent, legal and regulatory frameworks, and interpretation of complex results. In the Indian setting, rapid growth in genetic testing outpaces current policy and infrastructure, raising concerns about data privacy, cost, and protection from genetic discrimination. As genomic medicine continues to expand, nephrologists have an important role in advocating responsible testing practices and supporting patients through complex genetic information.

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Publication Details

Journal
Indian Journal of Nephrology
Published
2025-11-25
DOI
https://doi.org/10.25259/ijn_461_2025
Primary Topic
Genomics and Rare Diseases
Type
article
Field-Weighted Citation Impact
0.00
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article

Genetic Counseling in Nephrology: Challenges and Opportunities

Jordan G. Nestor, Matthew D. Gross
Indian Journal of Nephrology
Genomics and Rare Diseases
article

Genetic Counseling in Nephrology: Challenges and Opportunities

Jordan G. Nestor, Matthew D. Gross
article en

Abstract

Genetic testing is increasingly used in nephrology to diagnose hereditary kidney diseases, guide therapy, and inform transplant decisions. However, integrating genetic data into routine care presents ethical, logistical, and psychosocial challenges. This review outlines the key elements of genetic counseling in nephrology, including testing modalities, informed consent, legal and regulatory frameworks, and interpretation of complex results. In the Indian setting, rapid growth in genetic testing outpaces current policy and infrastructure, raising concerns about data privacy, cost, and protection from genetic discrimination. As genomic medicine continues to expand, nephrologists have an important role in advocating responsible testing practices and supporting patients through complex genetic information.

Indian Journal of NephrologyVol. 36
Johns Hopkins University (US), Johns Hopkins Medicine (US), Johns Hopkins Hospital (US), Columbia University (US)
Openalex Percentile: Top 61%
Genomics and Rare Diseases
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