Enhanced lubricin secretion by human synovial mesenchymal stem cells compared to adipose mesenchymal stem cells
More lubricin was secreted from human synovial MSCs than from adipose MSCs in the majority of donors examined. These findings support the potential therapeutic advantages of using synovial MSCs for osteoarthritis treatment.
Authors
- Yusuke Nakagawa (ORCID: https://orcid.org/0000-0001-5523-0856)
- Tetsuya Takakuwa (ORCID: https://orcid.org/0000-0002-9660-9384)
- Ichiro Sekiya (ORCID: https://orcid.org/0000-0002-6331-722X)
- Nobutake Ozeki (ORCID: https://orcid.org/0000-0002-2927-7930)
- Kentaro Endo (ORCID: https://orcid.org/0000-0003-4790-4632)
- Hideyuki Koga (ORCID: https://orcid.org/0000-0003-4574-1796)
- Makoto Tomita (ORCID: https://orcid.org/0000-0003-3553-1701)
Institutions
- Tokyo Medical and Dental University (JP)
- Regenerative Medicine Institute (MX)
- Yokohama City University (JP)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2025-11-26
- DOI
- https://doi.org/10.1186/s13287-025-04809-1
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 0.00