Factors Influencing Postoperative Outcomes in Children With Ureteropelvic Junction Obstruction

Ureteropelvic junction obstruction (UPJO) is a common urologic disorder in children. Accurate assessment of renal function, both preoperatively and postoperatively, is crucial for prognosis. Previous studies have primarily focused on postoperative function using univariate analysis. This study aimed to identify alternative assessment approaches. A retrospective study was conducted on 150 pediatric UPJO patients who underwent laparoscopic pyeloplasty. Multivariate logistic regression was performed to analyze factors influencing renal recovery, with improvement in renal morphology on ultrasonography as the outcome. Advanced age, prolonged hydronephrosis duration, overweight, and elevated serum creatinine levels (<i>P</i> < .05) were identified as significant risk factors for poor postoperative recovery. Younger age, shorter disease duration, normal serum creatinine levels, and healthy weight are associated with better postoperative recovery in UPJO patients. These findings highlight the importance of early intervention to optimize recovery.

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Journal
Clinical Pediatrics
Published
2025-11-26
DOI
https://doi.org/10.1177/00099228251381508
Primary Topic
Pediatric Urology and Nephrology Studies
Type
article
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article

Factors Influencing Postoperative Outcomes in Children With Ureteropelvic Junction Obstruction

Li Zhang, Deying Zhang
Clinical Pediatrics
Pediatric Urology and Nephrology Studies
article

Factors Influencing Postoperative Outcomes in Children With Ureteropelvic Junction Obstruction

Li Zhang, Deying Zhang
article en

Abstract

Ureteropelvic junction obstruction (UPJO) is a common urologic disorder in children. Accurate assessment of renal function, both preoperatively and postoperatively, is crucial for prognosis. Previous studies have primarily focused on postoperative function using univariate analysis. This study aimed to identify alternative assessment approaches. A retrospective study was conducted on 150 pediatric UPJO patients who underwent laparoscopic pyeloplasty. Multivariate logistic regression was performed to analyze factors influencing renal recovery, with improvement in renal morphology on ultrasonography as the outcome. Advanced age, prolonged hydronephrosis duration, overweight, and elevated serum creatinine levels (<i>P</i> < .05) were identified as significant risk factors for poor postoperative recovery. Younger age, shorter disease duration, normal serum creatinine levels, and healthy weight are associated with better postoperative recovery in UPJO patients. These findings highlight the importance of early intervention to optimize recovery.

Clinical PediatricsVol. 65(2)
Sichuan University (CN), West China Second University Hospital of Sichuan University (CN), Children's Hospital of Chongqing Medical University (CN), Chongqing Medical University (CN)
Openalex Percentile: Top 52%
Pediatric Urology and Nephrology Studies
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Factors Influencing Postoperative Outcomes in Children With Ureteropelvic Junction Obstruction — Li Zhang, Deying Zhang · Clinical Pediatrics (2025) | TGRS Research Map | TGRS