Contemporary Cleveland Clinic experience of fungal infective endocarditis: a focus on imaging and outcomes
We present the largest contemporary cohort study of fungal IE to date. Rates of complicated infection in fungal IE were high. Multimodality imaging with transesophageal echocardiography and computed tomography was critical in diagnosis. Although useful in identifying peripheral complications, nuclear studies may have lower sensitivity in identifying fungal IE, and further research is warranted in this population. While still elevated, 1-year mortality rates (30%) were significantly lower in our patient cohort than previously reported.
Authors
- Alice Haouzi (ORCID: https://orcid.org/0000-0002-6336-3074)
- Gösta Pettersson
- Nabin K. Shrestha (ORCID: https://orcid.org/0000-0001-6766-9874)
- Haytham Elgharably (ORCID: https://orcid.org/0000-0002-8124-0123)
- Shinya Unai (ORCID: https://orcid.org/0000-0001-6844-073X)
- Bo Xu (ORCID: https://orcid.org/0000-0002-2985-7468)
- Steven M. Gordon (ORCID: https://orcid.org/0000-0001-5571-2118)
- Yuichiro Okushi (ORCID: https://orcid.org/0009-0004-8534-6760)
- Brian P. Griffin (ORCID: https://orcid.org/0000-0001-6831-8611)
- Thomas G. Fraser
- Marijan Koprivanac (ORCID: https://orcid.org/0009-0004-6755-3037)
Institutions
- Cleveland Clinic (US)
Publication Details
- Journal
- European Heart Journal - Imaging Methods and Practice
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1093/ehjimp/qyaf143
- Primary Topic
- Antifungal resistance and susceptibility
- Type
- article
- Field-Weighted Citation Impact
- 0.00