DcR3, stabilized by the RNA-binding protein IGF2BP2, promotes proliferation, invasion, and migration of trophoblast cells and facilitates angiogenesis

Collectively, our study suggests that IGF2BP2-stabilized DcR3 promotes the proliferation, migration, invasion, and tube formation of trophoblast cells.

Authors

Po Zhao (ORCID: https://orcid.org/0000-0001-7362-7670)
Xiuwei Liu (ORCID: https://orcid.org/0000-0002-7381-9207)
Dan Li (ORCID: https://orcid.org/0000-0002-6332-1093)

Institutions

Tianjin Nankai Hospital (CN)

Publication Details

Journal: BMC Pregnancy and Childbirth
Published: 2025-11-26
DOI: https://doi.org/10.1186/s12884-025-08521-z
Primary Topic: Pregnancy and preeclampsia studies
Type: article
Field-Weighted Citation Impact: 0.00

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article

DcR3, stabilized by the RNA-binding protein IGF2BP2, promotes proliferation, invasion, and migration of trophoblast cells and facilitates angiogenesis

Po Zhao, Xiuwei Liu, Dan Li

Nov 26, 2025

BMC Pregnancy and Childbirth

Pregnancy and preeclampsia studies

article

DcR3, stabilized by the RNA-binding protein IGF2BP2, promotes proliferation, invasion, and migration of trophoblast cells and facilitates angiogenesis

Po Zhao, Xiuwei Liu, Dan Li

November 26, 2025article en

Abstract

Collectively, our study suggests that IGF2BP2-stabilized DcR3 promotes the proliferation, migration, invasion, and tube formation of trophoblast cells.

BMC Pregnancy and ChildbirthVol. 26(1)

Tianjin Nankai Hospital (CN)

Openalex Percentile: Top 53%

Pregnancy and preeclampsia studies

DOI Open Access PDF OpenAlex

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DcR3, stabilized by the RNA-binding protein IGF2BP2, promotes proliferation, invasion, and migration of trophoblast cells and facilitates angiogenesis — Po Zhao, Xiuwei Liu, et al. · BMC Pregnancy and Childbirth (2025) | TGRS Research Map | TGRS