Case - Long-term management of oligo-progressive metastatic castrate sensitive prostate cancer with recurrence-directed radiotherapy

RDT includes stereotactic body radiation therapy (SBRT) to precisely deliver high-dose radiation to metastatic sites with or without concomitant systemic therapy, elective nodal irradiation, and surgery.SBRT has shown promising efficacy in managing oligometastatic disease in various cancer types.This case report details a patient with CSPC who presented with episodes of oligoprogression, resisted treatment with standard of care ADT over a period of 9 years, and was managed with nine courses of RDT with limited ADT.It highlights the potential of RDT in addressing some therapeutic challenges posed by progressing metastatic PC.