The role of stress in the comorbidity of migraine and other chronic primary pain
Stress may be a key driver of migraine and CPP comorbidities. Stress induced preclinical models support mechanism exploration, and stress-targeted therapies hold promise for improving patient prognosis. Future research should deepen mechanistic studies and optimize models/therapies to enhance clinical care.
Authors
- Dong‐Yuan Cao (ORCID: https://orcid.org/0000-0002-3994-2885)
- Simon Akerman (ORCID: https://orcid.org/0000-0002-6577-6825)
- Shijie Zhao (ORCID: https://orcid.org/0009-0006-2457-4908)
- Qi Zhang (ORCID: https://orcid.org/0000-0002-9594-1991)
- Tingting Wang (ORCID: https://orcid.org/0000-0002-1774-1783)
Institutions
- University of Maryland, Baltimore (US)
- Shaanxi University of Chinese Medicine (CN)
- Xi'an Jiaotong University (CN)
Publication Details
- Journal
- Headache The Journal of Head and Face Pain
- Published
- 2025-11-26
- DOI
- https://doi.org/10.1111/head.70004
- Primary Topic
- Migraine and Headache Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00