Combined Influence of Depressive Symptoms and Estimated Glomerular Filtration Rate on Cognition Decline in US Adults

Both depressive symptoms and reduced eGFR are independent risk factors for cognitive decline, and their coexistence markedly amplifies risk, particularly in females. These findings highlight the importance of integrated screening and intervention for mental and renal health in older adults.

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Publication Details

Journal
Brain and Behavior
Published
2025-11-26
DOI
https://doi.org/10.1002/brb3.70997
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Combined Influence of Depressive Symptoms and Estimated Glomerular Filtration Rate on Cognition Decline in US Adults

Yue Yang, Sifan Chen, Qinwen Fei, Jie Li et al.
Brain and Behavior
Dementia and Cognitive Impairment Research
article

Combined Influence of Depressive Symptoms and Estimated Glomerular Filtration Rate on Cognition Decline in US Adults

Yue Yang, Sifan Chen, Qinwen Fei, Jie Li, Tian Lv, Yuxin Yang, Yu‐Ping He, Haoxiang Hu
article en

Abstract

Both depressive symptoms and reduced eGFR are independent risk factors for cognitive decline, and their coexistence markedly amplifies risk, particularly in females. These findings highlight the importance of integrated screening and intervention for mental and renal health in older adults.

Brain and BehaviorVol. 15(12)
Shaoxing University (CN), Wenzhou Medical University (CN), Lishui Central Hospital (CN), Zhujiang Hospital (CN), Lishui City People's Hospital (CN), Yuxian People's Hospital (CN)
Openalex Percentile: Top 57%
Dementia and Cognitive Impairment Research
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