Integrating explainable AI with clinical features to enhance ADHD diagnostic understanding
Integrating multimodal clinical features with transparent ML methods provides interpretable, clinically aligned insights into adult ADHD diagnosis. The combined SHAP-EDA approach identifies actionable thresholds, clarifies differential feature contributions, and highlights the importance of comorbidity and demographic context in diagnostic evaluation. These findings support a patient-centred, data-driven framework for improving diagnostic consistency in clinical practice. Future work should focus on multi-site validation and temporal analyses to assess generalisability and stability of feature influences over time.
Authors
- Hafiz Muhammad Shakeel (ORCID: https://orcid.org/0000-0003-2307-2763)
- Marios Adamou
- Georgia Antoniou (ORCID: https://orcid.org/0000-0003-0576-2365)
Institutions
- South West Yorkshire Partnership NHS Foundation Trust (GB)
- Leeds Beckett University (GB)
Publication Details
- Journal
- Frontiers in Psychiatry
- Published
- 2025-11-26
- DOI
- https://doi.org/10.3389/fpsyt.2025.1706216
- Citations
- 1
- Primary Topic
- Attention Deficit Hyperactivity Disorder
- Type
- article
- Field-Weighted Citation Impact
- 1.47
Funders
- Leeds Beckett University