Matched-Pair Analysis of Survival in the Patients with Oropharyngeal Squamous Cell Carcinoma Treated with Radiotherapy or Concurrent Chemoradiotherapy Versus Surgical-Based Treatment
These findings indicate that RT/CRT provides superior survival outcomes and better control of distant metastasis and second primary tumors compared with surgery in HPV-negative OPSCC, particularly in stage III disease. RT/CRT should be considered an effective organ-preserving option for this population.
Authors
- Daniel Pedregal‐Mallo (ORCID: https://orcid.org/0000-0001-8899-7957)
- Juan Pablo Rodrigo (ORCID: https://orcid.org/0000-0003-3063-0890)
- María Pilar Solís-Hernández (ORCID: https://orcid.org/0000-0002-0295-804X)
- Maria Ángeles de la Rúa
- Pilar Blay (ORCID: https://orcid.org/0000-0002-1772-2216)
- José Luís Llorente (ORCID: https://orcid.org/0000-0001-7713-5526)
- Fernando López (ORCID: https://orcid.org/0000-0001-7019-9746)
- Sonia Blanco
- Patricia García‐Cabo (ORCID: https://orcid.org/0000-0003-2542-163X)
Institutions
- Hospital Universitario Central de Asturias (ES)
- Instituto de Investigación Sanitaria del Principado de Asturias (ES)
Publication Details
- Journal
- Cancers
- Published
- 2025-11-26
- DOI
- https://doi.org/10.3390/cancers17233779
- Primary Topic
- Head and Neck Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00