DNA Methylation Algorithms of Aging and Incident Cardiovascular Disease: A Prospective Cohort Study
Zhang_DNAmAge, methylation Pace of Aging, and DNAmGrimAgeAcc function as independent predictors of incident CVD. These epigenetic biomarkers may improve early CVD detection and risk stratification in aging populations.
Authors
- Xian Cui (ORCID: https://orcid.org/0009-0000-1669-9467)
- Hui Zhang (ORCID: https://orcid.org/0000-0002-7358-5375)
- Yaqian Xu (ORCID: https://orcid.org/0000-0001-5890-3446)
- Zhaojun Wang (ORCID: https://orcid.org/0000-0003-2853-1850)
- Shiqun Sun (ORCID: https://orcid.org/0000-0002-1848-4782)
- Xiangwei Li (ORCID: https://orcid.org/0000-0002-9450-7771)
- Chongyu Ding (ORCID: https://orcid.org/0000-0001-5371-1162)
- Caitan Yi
Institutions
- Shanghai Jiao Tong University (CN)
- Ruijin Hospital (CN)
- Shanghai Children's Medical Center (CN)
- Hainan Medical University (CN)
Publication Details
- Journal
- Journal of the American Heart Association
- Published
- 2025-11-26
- DOI
- https://doi.org/10.1161/jaha.125.045545
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 0.00