Compound adsorption device in pathogen reduction technology removes multiple drugs from plasma components

The INTERCEPT PRT plasma kit CAD effectively removed multiple drug classes, suggesting a potential role in mitigating drug contamination in transfusable plasma products. These findings may support the reconsideration of some medication-based donor deferrals where the risk-benefit of donor safety and product efficacy favors collection.

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Publication Details

Journal
Transfusion
Published
2025-11-26
DOI
https://doi.org/10.1111/trf.18485
Primary Topic
Blood donation and transfusion practices
Type
article
Field-Weighted Citation Impact
0.00

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article

Compound adsorption device in pathogen reduction technology removes multiple drugs from plasma components

Waseem Q. Anani, B. Greenwall, K. Reeder
Transfusion
Blood donation and transfusion practices
article

Compound adsorption device in pathogen reduction technology removes multiple drugs from plasma components

Waseem Q. Anani, B. Greenwall, K. Reeder
article en

Abstract

The INTERCEPT PRT plasma kit CAD effectively removed multiple drug classes, suggesting a potential role in mitigating drug contamination in transfusable plasma products. These findings may support the reconsideration of some medication-based donor deferrals where the risk-benefit of donor safety and product efficacy favors collection.

TransfusionVol. 66(1)
University of Utah (US), ARUP Laboratories (United States) (US)
Partenariat Canadien Contre Le Cancer, National Institutes of Health, Center for AIDS Research, University of Washington, University of North Carolina at Chapel Hill
Openalex Percentile: Top 51%
Blood donation and transfusion practices
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