Intracellular Osteopontin of Macrophages Promotes Carotid Plaques Formation by Inducing Foam Cells and Releasing Proinflammatory Cytokines
Intracellular osteopontin of macrophages promotes plaque formation by inducing foam cells and releasing proinflammatory cytokines. Our data provide novel mechanistical insight and therapeutic strategy on atherosclerotic carotid plaque.
Authors
- Tao‐Sheng Li (ORCID: https://orcid.org/0000-0002-7653-8873)
- Weimin Zhou (ORCID: https://orcid.org/0000-0003-3086-6692)
- Zisheng Huang (ORCID: https://orcid.org/0009-0000-8770-661X)
- Han Nie (ORCID: https://orcid.org/0009-0009-5392-6089)
- Geng Liu (ORCID: https://orcid.org/0000-0002-6751-3084)
- Yan Chen (ORCID: https://orcid.org/0000-0003-3808-1259)
- Wei‐Hang Lu
Institutions
- University of Nagasaki (JP)
- Nanchang University (CN)
- Second Affiliated Hospital of Nanchang University (CN)
- Nagasaki University (JP)
Publication Details
- Journal
- Journal of the American Heart Association
- Published
- 2025-11-26
- DOI
- https://doi.org/10.1161/jaha.125.041336
- Citations
- 1
- Primary Topic
- Bone and Dental Protein Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.67