How to Safely Deliver Stereotactic Ablative Radiotherapy With High-Dose or Multi-agent Systemic Therapy

SABR given concurrently with multi-agent and high-dose systemic therapy during the off week of therapy is a safe and efficacious option. This treatment technique allows patients to remain on systemic therapy without any interruptions. Therefore, SABR can be a preferred local ablative treatment for patients with oligometastatic and oligoprogressive cancer while on concurrent systemic therapy.

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Publication Details

Journal
Cureus
Published
2025-11-26
DOI
https://doi.org/10.7759/cureus.97847
Primary Topic
Hepatocellular Carcinoma Treatment and Prognosis
Type
article
Field-Weighted Citation Impact
0.00
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article

How to Safely Deliver Stereotactic Ablative Radiotherapy With High-Dose or Multi-agent Systemic Therapy

Mark E. Bernard
Cureus
Hepatocellular Carcinoma Treatment and Prognosis
article

How to Safely Deliver Stereotactic Ablative Radiotherapy With High-Dose or Multi-agent Systemic Therapy

Mark E. Bernard
article en

Abstract

SABR given concurrently with multi-agent and high-dose systemic therapy during the off week of therapy is a safe and efficacious option. This treatment technique allows patients to remain on systemic therapy without any interruptions. Therefore, SABR can be a preferred local ablative treatment for patients with oligometastatic and oligoprogressive cancer while on concurrent systemic therapy.

CureusVol. 17(11)
University of Kentucky (US)
Openalex Percentile: Top 52%
Hepatocellular Carcinoma Treatment and Prognosis
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How to Safely Deliver Stereotactic Ablative Radiotherapy With High-Dose or Multi-agent Systemic Therapy — Mark E. Bernard · Cureus (2025) | TGRS Research Map | TGRS