Exploring circRNA_19601 as a therapeutic target in diabetic neuropathic pain: Insights from rat and cell models
Pregabalin mitigates mechanical and thermal pain in diabetic rats. It does so by reversing decreased pain thresholds and modifying the expression of circ19601. This, in turn, impacts miR-324-5p and pain-related proteins, leading to improvements in body weight and blood glucose levels.
Authors
- Jianlin Ge
- Qian Su (ORCID: https://orcid.org/0000-0003-4351-2631)
- Xuefeng Yang (ORCID: https://orcid.org/0000-0002-6787-4437)
- Jian-Yun Ge
- Hong Xie (ORCID: https://orcid.org/0009-0006-4179-817X)
- Xin Sun (ORCID: https://orcid.org/0009-0003-6305-4479)
- Zenghui Liu (ORCID: https://orcid.org/0000-0002-3159-7183)
- Boxiang Du (ORCID: https://orcid.org/0000-0002-9089-1884)
Institutions
- Nantong University (CN)
- Soochow University (CN)
- Affiliated Hospital of Nantong University (CN)
- Second Affiliated Hospital of Soochow University (CN)
- Second Affiliated Hospital of Nantong University
Publication Details
- Journal
- Molecular Pain
- Published
- 2025-11-26
- DOI
- https://doi.org/10.1177/17448069251405077
- Primary Topic
- Circular RNAs in diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00