An autoencoder and vision transformer based interpretability analysis on the performance differences in automated staging of second and third molars
The practical adoption of deep learning in high-stakes forensic applications, such as dental age estimation, is often limited by the 'black box' nature of the models. This study introduces a framework designed to enhance both performance and transparency in this context. We use a notable performance disparity in the automated staging of mandibular second (tooth 37) and third (tooth 38) molars as a case study. The proposed framework, which combines a convolutional autoencoder (AE) with a Vision Transformer (ViT), improves classification accuracy for both teeth over a baseline ViT, increasing from 0.712 to 0.815 for tooth 37 and from 0.462 to 0.543 for tooth 38. Beyond improving performance, the framework provides multi-faceted diagnostic insights. Analysis of the AE's latent space metrics and image reconstructions indicates that the remaining performance gap is data-centric, suggesting high intra-class morphological variability in the tooth 38 dataset is a primary limiting factor. This work highlights the insufficiency of relying on a single mode of interpretability, such as attention maps, which can appear anatomically plausible yet fail to identify underlying data issues. By offering a methodology that both enhances accuracy and provides evidence for why a model may be uncertain, this framework serves as a more robust tool to support expert decision-making in forensic age estimation.
Authors
- Jannick De Tobel (ORCID: https://orcid.org/0000-0002-8846-7339)
- Peter D. Claes (ORCID: https://orcid.org/0000-0001-9489-9819)
- Patrick Thevissen (ORCID: https://orcid.org/0000-0003-0890-6264)
- Barkın Büyükçakır (ORCID: https://orcid.org/0000-0001-5694-6100)
- Dirk Vandermeulen (ORCID: https://orcid.org/0000-0002-4052-5296)
Institutions
- Ghent University Hospital (BE)
- Ghent University (BE)
- KU Leuven (BE)
Publication Details
- Journal
- Scientific Reports
- Published
- 2025-11-26
- DOI
- https://doi.org/10.1038/s41598-025-26121-x
- Primary Topic
- Forensic Anthropology and Bioarchaeology Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- KU Leuven