Targeting of NF‐κB/NLRP3 Axis in Gestational Diabetes Mellitus

The NLRP3/NF-κB axis plays a pivotal role in mediating inflammation and insulin resistance in GDM. Targeting this pathway may offer a promising therapeutic strategy for preventing or managing GDM. However, further research is needed to fully elucidate its molecular interactions and validate potential pharmacological interventions.

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Publication Details

Journal
American Journal of Reproductive Immunology
Published
2025-11-26
DOI
https://doi.org/10.1111/aji.70188
Primary Topic
Gestational Diabetes Research and Management
Type
article
Field-Weighted Citation Impact
0.00
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article

Targeting of NF‐κB/NLRP3 Axis in Gestational Diabetes Mellitus

Ali I. Al‐Gareeb, Thabat J. Al‐Maiahy, Gaber El‐Saber Batiha, Duaa Eliwa et al.
American Journal of Reproductive Immunology
Gestational Diabetes Research and Management
article

Targeting of NF‐κB/NLRP3 Axis in Gestational Diabetes Mellitus

Ali I. Al‐Gareeb, Thabat J. Al‐Maiahy, Gaber El‐Saber Batiha, Duaa Eliwa, Ahmad Mahmoud Saleh, Hassanat Ramadan Abdel‐Aziz, Asmaa Morgan Farahat Khatap, Hayder Mutter Al-Kuraishy
article en

Abstract

The NLRP3/NF-κB axis plays a pivotal role in mediating inflammation and insulin resistance in GDM. Targeting this pathway may offer a promising therapeutic strategy for preventing or managing GDM. However, further research is needed to fully elucidate its molecular interactions and validate potential pharmacological interventions.

American Journal of Reproductive ImmunologyVol. 94(6)
Suez Canal University (EG), Prince Sattam Bin Abdulaziz University (SA), Mustansiriyah University (IQ), Damanhour University (EG), Zagazig University (EG), Tanta University (EG), University of Alkafeel (IQ)
Openalex Percentile: Top 53%
Gestational Diabetes Research and Management
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