Characteristics Associated With <scp>EuroLupus</scp> Versus Modified National Institutes of Health Cyclophosphamide Regimen Use in Children and Young Adults With Lupus Nephritis
For children and young adults with LN requiring CYC, use of the EuroLupus regimen increased over time and is associated with demographic and clinical factors such as race or Hispanic ethnicity, renal impairment, and absence of neuropsychiatric involvement. The differences in regimen use with severe renal impairment and neuropsychiatric lupus highlight areas for future study in CYC dosing.
Authors
- Nicole Ling (ORCID: https://orcid.org/0000-0002-9555-9792)
- Meredith Riebschleger
- Jennifer C. Cooper (ORCID: https://orcid.org/0000-0002-7673-6562)
- Stacy P. Ardoin (ORCID: https://orcid.org/0000-0003-4239-3634)
- Aliese Sarkissian
- Marinka Twilt (ORCID: https://orcid.org/0000-0003-1954-2822)
- Julia Shalen (ORCID: https://orcid.org/0009-0000-7708-5899)
- Scott E. Wenderfer (ORCID: https://orcid.org/0000-0002-8991-8277)
- Kelly Rouster‐Stevens (ORCID: https://orcid.org/0000-0002-7855-9168)
- Kristen Miller
- Emily Hause
- Rebecca E. Sadun (ORCID: https://orcid.org/0000-0001-7768-3565)
- Wenru Zhou
- William Daniel Soulsby (ORCID: https://orcid.org/0000-0003-1873-3520)
- Christine Bearer (ORCID: https://orcid.org/0009-0008-8440-8746)
- Joyce Hui‐Yuen (ORCID: https://orcid.org/0000-0002-0545-906X)
- Laura B. Lewandowski (ORCID: https://orcid.org/0000-0002-4253-2545)
- Eveline Y. Wu (ORCID: https://orcid.org/0000-0002-6394-6843)
- Maria Pereira (ORCID: https://orcid.org/0000-0003-4724-6385)
- Christine Wang (ORCID: https://orcid.org/0000-0002-8706-7157)
Institutions
- University of North Carolina at Chapel Hill (US)
- Fairview Health Services (US)
- University of British Columbia (CA)
- Johns Hopkins University (US)
- Duke University (US)
- University of California, San Francisco (US)
- Johns Hopkins Medicine (US)
- Alberta Children's Hospital (CA)
- National Institute of Arthritis and Musculoskeletal and Skin Diseases (US)
- Akron Children's Hospital (US)
- Ohio State University Hospital (US)
- Cohen Children's Medical Center (US)
- Children's Healthcare of Atlanta (US)
- Texas Children's Hospital (US)
- C. S. Mott Children's Hospital (US)
- University of Minnesota Children's Hospital (US)
- University of Colorado Anschutz Medical Campus (US)
- The Ohio State University (US)
Publication Details
- Journal
- ACR Open Rheumatology
- Published
- 2025-11-26
- DOI
- https://doi.org/10.1002/acr2.70132
- Primary Topic
- Systemic Lupus Erythematosus Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00