Toward targeted dementia prevention: Population attributable fractions and risk profiles in Germany
36% of dementia cases in Germany are linked to modifiable risk factors.A 15% reduction in risk factor prevalence could prevent 170,000 cases by 2050.Key contributors: depression, hearing loss, low education, and obesity.Data-driven risk profiles identified (e.g., metabolic, sensory, low-risk).Risk profiles strongly associated with sociodemographic characteristics.
Authors
- Jochen René Thyrian (ORCID: https://orcid.org/0000-0001-6889-693X)
- Iris Blotenberg (ORCID: https://orcid.org/0000-0002-2273-5564)
Institutions
- Brigham and Women's Hospital (US)
- Harvard University (US)
- Universitätsmedizin Greifswald (DE)
- German Center for Neurodegenerative Diseases (DE)
Publication Details
- Journal
- Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring
- Published
- 2025-10-01
- DOI
- https://doi.org/10.1002/dad2.70225
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00