Interpretable and reproducible machine learning model for coronary calcification and segment-level stenoses stratification on computed tomography angiography
Stable imaging features provide a reference for future ML-based coronary quantitatively assessments. Interpretable ML models demonstrated promising performance in quantifying coronary calcification and segment-level stenoses.
Authors
- Xiaowei Zhou (ORCID: https://orcid.org/0000-0003-4940-6936)
- Zheng Jin (ORCID: https://orcid.org/0000-0003-3191-4473)
- Y F Li (ORCID: https://orcid.org/0009-0007-0060-2166)
- L. Escudero (ORCID: https://orcid.org/0000-0003-3464-9206)
- Yancheng Xu (ORCID: https://orcid.org/0000-0002-3298-5110)
- Jonathan Richard Weir-McCall (ORCID: https://orcid.org/0000-0001-5842-842X)
- Yuan Huang (ORCID: https://orcid.org/0000-0002-2044-099X)
- Zeyu Gao (ORCID: https://orcid.org/0000-0003-2365-8318)
- James H.F. Rudd (ORCID: https://orcid.org/0000-0003-2243-3117)
- David E. Newby (ORCID: https://orcid.org/0000-0001-7971-4628)
- Hongqiu Wang
- Guangming Wang (ORCID: https://orcid.org/0000-0001-7180-1559)
- Zhongzhao Teng (ORCID: https://orcid.org/0000-0003-3973-6157)
- Ziming Wang (ORCID: https://orcid.org/0000-0003-1463-7590)
- Jian Chen (ORCID: https://orcid.org/0000-0002-1694-7763)
- Kaixuan Li (ORCID: https://orcid.org/0000-0001-5244-383X)
- Yiran Wei (ORCID: https://orcid.org/0000-0003-1791-6050)
- Michelle C. Williams
Institutions
- Central South University (CN)
- King's College London (GB)
- Hong Kong University of Science and Technology (HK)
- University of Cambridge (GB)
- Royal Papworth Hospital (GB)
- British Heart Foundation (GB)
- Cambridge School (PT)
- Xiangya Hospital Central South University (CN)
- Fujian University of Technology (CN)
- University of Edinburgh (GB)
Publication Details
- Journal
- BMC Medicine
- Published
- 2025-11-26
- DOI
- https://doi.org/10.1186/s12916-025-04478-0
- Citations
- 1
- Primary Topic
- Cardiac Imaging and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 1.36
Funders
- Scottish Government
- National Institute for Health and Care Research
- British Heart Foundation
- Cambridge Trust
- Chief Scientist Office, Scottish Government Health and Social Care Directorate
- NIHR Cambridge Biomedical Research Centre