The effect of acetyl tributyl citrate on coronary heart disease: a comprehensive computational analysis
Our study predicted ATBC's potential mechanisms in CHD progression and identified key hub genes, notably MMP9, NLRP3, and PLAU. These findings provide novel molecular targets for future research and highlight the potential health risks of ATBC in everyday applications.
Authors
- Xu Ma (ORCID: https://orcid.org/0000-0001-7674-3589)
- Zhen Hua
- Feng Jiang (ORCID: https://orcid.org/0000-0001-6903-9761)
- Kaile Wang
- Yingying Liu (ORCID: https://orcid.org/0000-0002-0822-133X)
- Lei Zhang (ORCID: https://orcid.org/0009-0003-1693-0093)
- Jie Yu (ORCID: https://orcid.org/0000-0001-6345-2096)
- Shuxia Shi
Institutions
- Shandong University of Traditional Chinese Medicine (CN)
- Affiliated Hospital of Shandong University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- BMC Pharmacology and Toxicology
- Published
- 2025-11-26
- DOI
- https://doi.org/10.1186/s40360-025-01023-w
- Primary Topic
- Sirtuins and Resveratrol in Medicine
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Shandong University
- National Natural Science Foundation of China
- China Postdoctoral Science Foundation
- Natural Science Foundation of Shandong Province
- Liaoning University
- Liaoning University of Traditional Chinese Medicine