Metformin mitigates cisplatin-induced premature ovarian insufficiency via Sirt1/Nrf2 activation

Metformin may serve as a promising therapeutic agent to prevent POI by mitigating oxidative stress and apoptosis.

Authors

Xiaodong Li (ORCID: https://orcid.org/0000-0002-8896-946X)
Tao Geng (ORCID: https://orcid.org/0000-0001-7312-5013)
Jiabei Hao (ORCID: https://orcid.org/0000-0003-0999-3291)
Yang Sai (ORCID: https://orcid.org/0000-0002-5742-116X)
Xueping Liu (ORCID: https://orcid.org/0000-0002-7978-5028)
Yujing Wang (ORCID: https://orcid.org/0000-0002-0139-9514)
Ying Zheng (ORCID: https://orcid.org/0000-0002-5084-0142)
Zijie Fu (ORCID: https://orcid.org/0000-0002-9487-1477)
Qingya Ma