Inflammatory and neuroimmune imbalance in diabetic incontinence: insights from serum biomarker profiling
In diabetic urinary incontinence, 4-HNE showed the most consistent group-level separation-lower in DI compared with both Non-DI and healthy controls-whereas LL-37, elafin, VDR, and Aβ1-42 did not demonstrate Bonferroni-corrected pairwise differences. These preliminary findings highlight oxidative and neuroimmune alterations in diabetic incontinence and warrant validation in larger longitudinal studies.
Authors
- Gökhan Temeltaş (ORCID: https://orcid.org/0000-0001-7673-2206)
- Ali Can Albaz (ORCID: https://orcid.org/0000-0002-7725-1241)
- Talha Müezzi̇noğlu (ORCID: https://orcid.org/0000-0001-7799-008X)
- Oktay Üçer (ORCID: https://orcid.org/0000-0001-7912-0408)
- Funda Kosova (ORCID: https://orcid.org/0000-0001-8070-5067)
Institutions
- Manisa Celal Bayar University (TR)
Publication Details
- Journal
- BMC Urology
- Published
- 2025-11-26
- DOI
- https://doi.org/10.1186/s12894-025-01992-4
- Primary Topic
- Pelvic floor disorders treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Manisa Celal Bayar Üniversitesi