Chlorogenic acid mitigates acute respiratory distress syndrome via inhibition of the PI3K/AKT signalling pathway: an integrated analysis of bioinformatics and validation experiments
CGA alleviates ARDS by inhibiting the PI3K/AKT signaling pathway, thereby suppressing inflammation, regulating T-cell subtypes, and reducing NET formation.
Authors
- Guan Ye Nai
- Wei Zhou (ORCID: https://orcid.org/0000-0003-0435-7261)
- Zhenwei Wei (ORCID: https://orcid.org/0000-0001-7016-7787)
- Yu mei Huang
- Zhen Gan (ORCID: https://orcid.org/0000-0002-2914-4564)
- Min Wu (ORCID: https://orcid.org/0000-0003-0977-3600)
- Hui Li
- Rong Rong Liu
- Jie Wei (ORCID: https://orcid.org/0009-0000-7600-8779)
Institutions
- First Affiliated Hospital of GuangXi Medical University (CN)
- Affiliated Hospital of Youjiang Medical University for Nationalities (CN)
- Baise University (CN)
Publication Details
- Journal
- Annals of Medicine
- Published
- 2025-11-26
- DOI
- https://doi.org/10.1080/07853890.2025.2588840
- Primary Topic
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00