Catastrophic antiphospholipid syndrome following surgery for Libman–Sacks endocarditis: A case report and literature review

This case highlights the importance of recognising APS as the systemic autoimmune basis of LSE and the need for early immunologic and thrombotic evaluation in patients with unexplained valve lesions. Failure to identify underlying APS before surgery may increase the risk of CAPS and poor outcomes.

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Publication Details

Journal
Journal of Cardiothoracic Surgery
Published
2025-11-26
DOI
https://doi.org/10.1186/s13019-025-03692-4
Primary Topic
Systemic Lupus Erythematosus Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Catastrophic antiphospholipid syndrome following surgery for Libman–Sacks endocarditis: A case report and literature review

Y. Li, Qingyu Huang, Rui Shen
Journal of Cardiothoracic Surgery
Systemic Lupus Erythematosus Research
article

Catastrophic antiphospholipid syndrome following surgery for Libman–Sacks endocarditis: A case report and literature review

Y. Li, Qingyu Huang, Rui Shen
article en

Abstract

This case highlights the importance of recognising APS as the systemic autoimmune basis of LSE and the need for early immunologic and thrombotic evaluation in patients with unexplained valve lesions. Failure to identify underlying APS before surgery may increase the risk of CAPS and poor outcomes.

Journal of Cardiothoracic SurgeryVol. 20(1)
Fudan University (CN), Shanghai University of Traditional Chinese Medicine (CN), Shanghai Traditional Chinese Medicine Hospital (CN), Huashan Hospital (CN)
Openalex Percentile: Top 48%
Systemic Lupus Erythematosus Research
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