Construction of a Full-Length Infectious Clone Derived from Type O Foot-and-Mouth Disease Virus Isolated in South Korea for Vaccine Development with High Antigen Productivity
To the best of our knowledge, this is the first report describing the construction of an infectious clone derived from a field FMDV isolate in South Korea and its application in vaccine development. The O/Boeun/SKR/2017 infectious clone may serve as a genetic backbone for the rapid generation of new FMD vaccine candidates with high antigen productivity by substituting epitopes from other FMDV.
Authors
- Young-Joon Ko (ORCID: https://orcid.org/0000-0002-3436-8175)
- Gyeongmin Lee (ORCID: https://orcid.org/0000-0002-2721-9016)
- Jong-Hyeon Park (ORCID: https://orcid.org/0000-0003-0825-8121)
- Jae Young Kim (ORCID: https://orcid.org/0000-0003-0101-2620)
- Sun Young Park (ORCID: https://orcid.org/0000-0002-2784-513X)
- Sang Hyun Park (ORCID: https://orcid.org/0000-0003-0612-2562)
- Jong Sook Jin
Institutions
- Animal and Plant Quarantine Agency (KR)
Publication Details
- Journal
- Vaccines
- Published
- 2025-11-26
- DOI
- https://doi.org/10.3390/vaccines13121195
- Primary Topic
- Animal Disease Management and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Animal and Plant Quarantine Agency