Could GSTP1, PTEN and NKX3.1 gene expression be novel markers in the relationship between prostate cancer and epigenetics?
The findings of this investigation corroborated the notion that prospective novel markers, including GSTP1, PTEN, and NKX3.1, may serve predictive and prognostic functions in prostate cancer, hence enhancing the efficacy of PSA in its diagnosis. Dietary trends may influence the optimization of many epigenetic processes. Targeted therapeutic nutritional interventions designed to enhance gene expression will facilitate the formulation of prostate cancer prevention methods.
Authors
- Tevfik Koçak (ORCID: https://orcid.org/0000-0002-4096-6796)
- Yusuf Icer (ORCID: https://orcid.org/0000-0001-6488-4472)
- Nilüfer Acar Tek (ORCID: https://orcid.org/0000-0002-8772-9608)
- Süleyman Yeşil (ORCID: https://orcid.org/0000-0002-0437-9615)
- Mehmet Ali Ergün (ORCID: https://orcid.org/0000-0001-9696-0433)
Institutions
- Gümüşhane University (TR)
- Gazi University (TR)
- University of Edinburgh (GB)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-11-26
- DOI
- https://doi.org/10.1186/s12885-025-15077-w
- Primary Topic
- Glutathione Transferases and Polymorphisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Gazi Üniversitesi