β-lapachone impairs viability, migration, and epithelial–mesenchymal transition in mammary tumor spheroids
The natural compound β-lap has the potential to be a promising anticancer agent for breast cancer.
Authors
- FÁTIMA C. MAGALHÃES
- Pedro Paulo de Abreu Manso (ORCID: https://orcid.org/0000-0002-7255-0429)
- Cláudia Mara Lara Melo Coutinho (ORCID: https://orcid.org/0000-0002-5423-3032)
- Beatriz Matheus de Souza Gonzaga (ORCID: https://orcid.org/0000-0002-6862-7008)
- Edmilson José Maria (ORCID: https://orcid.org/0000-0002-4293-267X)
- Luciana Garzoni (ORCID: https://orcid.org/0000-0002-6527-0664)
- Laura Lacerda Coelho (ORCID: https://orcid.org/0000-0002-5242-9541)
- Debora Moraes da Silva (ORCID: https://orcid.org/0000-0002-3998-0435)
- Marcelo Alex Carvalho (ORCID: https://orcid.org/0000-0002-7053-0053)
- Matheus Menezes Vianna (ORCID: https://orcid.org/0000-0003-1879-1405)
- Roberto Rodrigues Ferreira (ORCID: https://orcid.org/0000-0001-5010-7007)
- Fernando Regla Vargas (ORCID: https://orcid.org/0000-0003-1106-4061)
- Rodrigo Rodrigues de Oliveira (ORCID: https://orcid.org/0000-0002-3145-4844)
Institutions
- State University of Norte Fluminense (BR)
- Instituto Nacional de Câncer - INCA (BR)
- Fundação Oswaldo Cruz (BR)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-11-26
- DOI
- https://doi.org/10.1186/s12885-025-15067-y
- Primary Topic
- Bioactive Compounds and Antitumor Agents
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro
- Fundação Oswaldo Cruz
- Foundation for Scientific and Technological Development in Health
- National Cancer Institute