Transcriptomic exploration combined with experimental validation: uncovering the potential value of biomarkers related to ammonia-induced cell death in hepatic ischemia–reperfusion injury
LCP1, SLC16A3, and RGS2 have been identified as biomarkers of HIRI. The study advances understanding of ACD-related genes signatures in HIRI and provides a foundation for future mechanistic research and therapeutic development.
Authors
- Junhao Xiao
- Benliang Mao (ORCID: https://orcid.org/0009-0004-6135-8134)
- Runyu Zhuang (ORCID: https://orcid.org/0009-0004-2105-446X)
- Fan Wu (ORCID: https://orcid.org/0000-0001-8621-9449)
- Yuan Wei (ORCID: https://orcid.org/0000-0003-3387-7549)
- Bailin Wang (ORCID: https://orcid.org/0000-0001-5873-171X)
- Yong Yan
Institutions
- Guiyang Medical University (CN)
- Jinan University (CN)
- Guhua Hospital (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-11-26
- DOI
- https://doi.org/10.1186/s40001-025-03450-1
- Primary Topic
- Organ Transplantation Techniques and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00