Modulating cerebrospinal fluid dynamics using pulsed photobiomodulation
This study establishes that PBM can modulate CSF flow in the healthy human brain in real time. This study also suggests that iPBM may be more efficient in CSF modulation due to the proximity to the olfactory system and the lack of melanin dependence. The influence of melanin on tPBM, the feasibility of iPBM and the dose dependence of both will require further investigation in healthy and patient populations.
Authors
- Xiaole Zhong (ORCID: https://orcid.org/0000-0002-8641-5658)
- Joanna X Chen (ORCID: https://orcid.org/0009-0005-1510-5651)
- J. Jean Chen
- Hannah Van Lankveld (ORCID: https://orcid.org/0009-0004-4800-5801)
- A Mathew (ORCID: https://orcid.org/0009-0002-1195-9316)
- Ariel Motsenyat
Institutions
- University of Toronto (CA)
- Baycrest Hospital (CA)
Publication Details
- Journal
- Brain stimulation
- Published
- 2025-11-26
- DOI
- https://doi.org/10.1016/j.brs.2025.102988
- Citations
- 3
- Primary Topic
- Laser Applications in Dentistry and Medicine
- Type
- article
- Field-Weighted Citation Impact
- 4.08
Funders
- Natural Sciences and Engineering Research Council of Canada