Risk of Late-Onset Depression in Long-Term Survivors of Breast, Prostate, and Colorectal Cancer
In this cohort study of long-term cancer survivors, Medicare and Medicaid dual eligibility, higher comorbidity burden, and preexisting anxiety were independently associated with greater risk of late-onset depression. These findings suggest that these risk factors may be used to proactively inform survivorship care during the transition from cancer surveillance to preventive care, which could reduce the risk of inconsistent follow-up care for survivors that may drive socioeconomic and racial and ethnic disparities in depression screening and treatment.
Authors
- Melissa Taylor (ORCID: https://orcid.org/0000-0002-2629-978X)
- Tendai Kwaramba
- Ira L. Leeds (ORCID: https://orcid.org/0000-0001-6572-8658)
- Andrea Silber (ORCID: https://orcid.org/0000-0002-3339-6959)
- Faiza Yasin (ORCID: https://orcid.org/0000-0003-3042-0826)
- Michael Cecchini (ORCID: https://orcid.org/0000-0003-3504-0128)
- Stephanie B. Wheeler (ORCID: https://orcid.org/0000-0002-3399-9047)
- Lisa P. Spees (ORCID: https://orcid.org/0000-0002-5680-9330)
- Terry Hyslop (ORCID: https://orcid.org/0000-0002-3930-8876)
- Rebecca Forman (ORCID: https://orcid.org/0000-0002-3012-4712)
- Michael Leapman (ORCID: https://orcid.org/0000-0002-0727-7614)
- Cary P. Gross (ORCID: https://orcid.org/0000-0002-4974-935X)
- Kevin Charles Oeffinger (ORCID: https://orcid.org/0000-0003-0806-7894)
- Michaela A. Dinan (ORCID: https://orcid.org/0000-0003-4849-4743)
- Sarah J. Westvold (ORCID: https://orcid.org/0009-0004-2060-2137)
- Shi-Yi Wang
- Jessica B. Long
Institutions
- University of North Carolina at Chapel Hill (US)
- Thomas Jefferson University (US)
- Duke University (US)
- Yale Cancer Center (US)
- Yale University (US)
- Sidney Kimmel Cancer Center (US)
- Duke Medical Center (US)
- UNC Lineberger Comprehensive Cancer Center
Publication Details
- Journal
- JAMA Network Open
- Published
- 2025-11-26
- DOI
- https://doi.org/10.1001/jamanetworkopen.2025.44812
- Citations
- 1
- Primary Topic
- Cancer survivorship and care
- Type
- article
- Field-Weighted Citation Impact
- 1.05