Oral indomethacin modifies small intestine biofilms and host-microbe interaction mediators

This is the first comprehensive characterization of the time-dependent changes in TLRs, AMPs and mucosal biofilm in NSAID-treated rats, which may help to identify new strategies for the treatment of enteropathy.

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Publication Details

Journal
Life Sciences
Published
2025-11-26
DOI
https://doi.org/10.1016/j.lfs.2025.124114
Primary Topic
Inflammatory Bowel Disease
Type
article
Field-Weighted Citation Impact
0.00
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article

Oral indomethacin modifies small intestine biofilms and host-microbe interaction mediators

Balázs Ligeti, Bence Ágg, Anna Jakab, Andrea Kelemen et al.
Life Sciences
Inflammatory Bowel Disease
article

Oral indomethacin modifies small intestine biofilms and host-microbe interaction mediators

Balázs Ligeti, Bence Ágg, Anna Jakab, Andrea Kelemen, Guillaume Le Cosquer, Gábor Kökény, Péter Ferdinandy, Nathalie Vergnolle, Samaneh Haghighi, Jean‐Paul Motta, András S. Tóth, Krisztián A. Kovács, Elodie Meunier, Eszter Ostorházi, Zsuzsanna O. Demeter, Zoltán Zádori, Barbara Hutka, Nóra Makra, Dóra Szabó, Arezoo Haghighi, Melissa Pannier, Klára Gyires, Gerda Wachtl, Lili Lengyel, Anna Zsidai
article en

Abstract

This is the first comprehensive characterization of the time-dependent changes in TLRs, AMPs and mucosal biofilm in NSAID-treated rats, which may help to identify new strategies for the treatment of enteropathy.

Life SciencesVol. 384
Semmelweis University (HU), Pázmány Péter Catholic University (HU)
Openalex Percentile: Top 61%
Inflammatory Bowel Disease
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Oral indomethacin modifies small intestine biofilms and host-microbe interaction mediators — Balázs Ligeti, Bence Ágg, et al. · Life Sciences (2025) | TGRS Research Map | TGRS