Meloxicam may induce nephrotoxicity in California sea lions (Zalophus californianus) with chronic domoic acid toxicosis
This is the first report of meloxicam-associated nephrotoxicity in pinnipeds. While multiple factors such as dehydration, nutrition, other medication, and/or compromised immune function may have contributed to the development of nephrotoxicity, further evaluation of renal effects of domoic acid as well as effects of NSAIDs is warranted in CSLs.
Authors
- Mark G. Papich (ORCID: https://orcid.org/0000-0002-7591-7898)
- Margaret E. Martinez (ORCID: https://orcid.org/0000-0001-9637-7117)
- Emily J. Trumbull (ORCID: https://orcid.org/0000-0001-5823-1459)
- Cara L. Field (ORCID: https://orcid.org/0000-0001-9283-0199)
- Mattison Peters (ORCID: https://orcid.org/0000-0003-0645-4233)
- Pádraig J. Duignan (ORCID: https://orcid.org/0000-0002-6565-4799)
Institutions
- Marine Mammal Center (US)
- North Carolina State University (US)
Publication Details
- Journal
- Journal of the American Veterinary Medical Association
- Published
- 2025-11-26
- DOI
- https://doi.org/10.2460/javma.25.08.0559
- Primary Topic
- Marine Toxins and Detection Methods
- Type
- article
- Field-Weighted Citation Impact
- 0.00