Immunodeficiency, HIV Viremia, and Incident Anal Cancer Among People With HIV in South Africa
Among 130 992 people with HIV (PWH) in South Africa, 60 anal cancers were diagnosed. Lower CD4 counts and, to a lesser extent, higher HIV RNA viral loads were associated with an increased anal cancer risk. Maintaining high CD4 counts may contribute to anal cancer prevention among PWH in South Africa.
Authors
- Yann Ruffieux (ORCID: https://orcid.org/0000-0002-0891-2448)
- Naomi Folb (ORCID: https://orcid.org/0000-0002-2667-0956)
- Eliane Rohner (ORCID: https://orcid.org/0000-0002-0554-2875)
- Gary Maartens (ORCID: https://orcid.org/0000-0003-3080-6606)
- JANET M. NOBLE
- Nathalie V. Fernández Villalobos (ORCID: https://orcid.org/0000-0001-7560-5256)
- Chido Chinogurei (ORCID: https://orcid.org/0000-0002-1560-7580)
- Matthias Egger (ORCID: https://orcid.org/0000-0001-7462-5132)
- Nicola Low (ORCID: https://orcid.org/0000-0003-4817-8986)
- Andreas D. Haas (ORCID: https://orcid.org/0000-0002-4849-181X)
Institutions
- University of Bern (CH)
- University of Cape Town (ZA)
- University of Zurich (CH)
- University of Bristol (GB)
- University Hospital of Zurich (CH)
- Institute of Social and Preventive Medicine (CH)
Publication Details
- Journal
- Open Forum Infectious Diseases
- Published
- 2025-11-10
- DOI
- https://doi.org/10.1093/ofid/ofaf693
- Primary Topic
- Cervical Cancer and HPV Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00