[18F]Fluorodeoxyglucose Positron Emission Tomography for Diagnosis and Monitoring of Acute <i>Staphylococcus aureus</i> Vascular Graft Infection in a Rat Model
FDG-PET differentiated untreated S. aureus-infected rats from uninfected ones but failed to monitor infection progression, as SUVmax declined over time despite a constant bacterial load. FDG-PET could not distinguish between uninfected rats and those with suppressed infection, likely due to reduced inflammation and encapsulation of the infection.
Authors
- Louise Kruse Jensen (ORCID: https://orcid.org/0000-0002-0372-4923)
- Cecilie Bay-Richter (ORCID: https://orcid.org/0000-0002-2254-4020)
- Nis Pedersen Jørgensen (ORCID: https://orcid.org/0000-0002-6153-2604)
- Mikkel Holm Vendelbo (ORCID: https://orcid.org/0000-0003-0431-2522)
- Emma Faddy (ORCID: https://orcid.org/0009-0003-9883-976X)
- C. Gadeberg (ORCID: https://orcid.org/0009-0007-8250-1421)
- Rikke Louise Meyer (ORCID: https://orcid.org/0000-0002-6485-5134)
- Lars Østergaard (ORCID: https://orcid.org/0000-0003-2459-0511)
- Mikkel Illemann Johansen (ORCID: https://orcid.org/0000-0002-3953-1621)
Institutions
- University of Copenhagen (DK)
- Copenhagen Business School (DK)
- Aarhus University (DK)
- Aarhus University Hospital (DK)
- Regional Hospital Randers (DK)
Publication Details
- Journal
- The Journal of Infectious Diseases
- Published
- 2025-11-26
- DOI
- https://doi.org/10.1093/infdis/jiaf594
- Primary Topic
- Infectious Aortic and Vascular Conditions
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Aarhus Universitet
- Aarhus Universitetshospital
- Institut for Klinisk Medicin, Aarhus Universitet
- Knud og Edith Eriksens Mindefond