Combining transcriptomics with network pharmacology to explore the mechanism of Yiqi Huoxue decoction against liver fibrosis
We reveal here the molecular mechanism and signaling pathway of YQHX in treating liver fibrosis by utilizing network pharmacology in conjunction with in vivo and in vitro experiments. The findings offer insights that may advance the clinical application of YQHX.
Authors
- Dandan Zhao (ORCID: https://orcid.org/0000-0001-5194-750X)
- Jia-Wei Cui (ORCID: https://orcid.org/0000-0002-2609-6034)
- Cong-Yue Zhang (ORCID: https://orcid.org/0000-0002-2055-1024)
- Yuemin Nan (ORCID: https://orcid.org/0000-0003-4192-099X)
- Ke Zhang (ORCID: https://orcid.org/0000-0002-8142-6702)
- Y. F. Mao (ORCID: https://orcid.org/0000-0003-3589-000X)
- Zhenhai Lin
Institutions
- Hebei Medical University (CN)
- Third Hospital of Hebei Medical University (CN)
- Hospital of Hebei Province (CN)
- First Affiliated Hospital of Zhengzhou University (CN)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-11-26
- DOI
- https://doi.org/10.1371/journal.pone.0337061
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00