The last dance of coupled plasma filtration adsorption (CPFA): Clinical outcomes, challenges, and perspectives in multiple organ support therapy
In this cohort, CPFA was feasible and safe, with possible hemodynamic and survival benefits when a sufficient plasma-treated volume was reached. Patient selection and optimized treatment delivery appear crucial. However, the retrospective design and lack of a control group limit definitive conclusions. Future research should focus on more effective and targeted extracorporeal strategies for immune modulation in critically ill patients.
Authors
- Gonzalo Ramírez‐Guerrero (ORCID: https://orcid.org/0000-0002-1696-9997)
- Cristian Pedreros‐Rosales (ORCID: https://orcid.org/0000-0002-1338-0503)
- Hans Müller-Ortíz (ORCID: https://orcid.org/0000-0003-4735-5856)
- Pilar Musalem (ORCID: https://orcid.org/0009-0009-2455-0668)
- Cristóbal Alvarado Livacic
Institutions
- University of Concepción (CL)
- Universidad Católica de la Santísima Concepción (CL)
- Hospital Las Higueras (CL)
Publication Details
- Journal
- The International Journal of Artificial Organs
- Published
- 2025-11-14
- DOI
- https://doi.org/10.1177/03913988251391998
- Citations
- 1
- Primary Topic
- Acute Kidney Injury Research
- Type
- article
- Field-Weighted Citation Impact
- 1.43