Less endocrine therapy in HR+/HER2- breast cancer: a nationwide trend despite unchanged guidelines

Despite unchanged guideline recommendations, fewer patients started ET over time. This trend, and regional variation, suggests that a more reticent approach by physicians to initiating ET for HR+/HER2- breast cancer may be contributing to it.

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Publication Details

Journal
The Breast
Published
2025-11-27
DOI
https://doi.org/10.1016/j.breast.2025.104664
Primary Topic
Breast Cancer Treatment Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Less endocrine therapy in HR+/HER2- breast cancer: a nationwide trend despite unchanged guidelines

José H. Volders, Eline E. F. Verreck, Sabine Siesling, Emily L. Postma et al.
The Breast
Breast Cancer Treatment Studies
article

Less endocrine therapy in HR+/HER2- breast cancer: a nationwide trend despite unchanged guidelines

José H. Volders, Eline E. F. Verreck, Sabine Siesling, Emily L. Postma, Thijs van Dalen, Anouk H. Eijkelboom, Tanja Oostergo, Dimitris Rizopoulos, Joyce Meijer
article en

Abstract

Despite unchanged guideline recommendations, fewer patients started ET over time. This trend, and regional variation, suggests that a more reticent approach by physicians to initiating ET for HR+/HER2- breast cancer may be contributing to it.

The BreastVol. 85
Erasmus MC (NL), University Medical Center Utrecht (NL), St. Antonius Ziekenhuis (NL), Diakonessenhuis hospital (NL), Netherlands Comprehensive Cancer Organisation (NL), Erasmus University Rotterdam (NL)
Openalex Percentile: Top 55%
Breast Cancer Treatment Studies
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