Left ventricular ejection fraction response after atrial fibrillation ablation: Clinical predictors and development of the PACED score
LVEF response post-AF ablation in patients with LVSD can be accurately predicted precatheter ablation with a bedside score. Left ventricular response depends primarily on substrate and conduction characteristics rather than pharmacotherapy in a guideline-directed medical therapy-optimized cohort. Late gadolinium enhancement on cardiac magnetic resonance is associated with an increased chance of being a nonresponder to ablation.
Authors
- Martín Thomas (ORCID: https://orcid.org/0000-0003-3533-4425)
- Brett Kennedy (ORCID: https://orcid.org/0000-0001-5018-5654)
- Nikhil Ahluwalia (ORCID: https://orcid.org/0000-0003-1257-5576)
- Amal Muthumala
- Christopher Patrick Uy (ORCID: https://orcid.org/0000-0003-1744-6300)
- Charles Butcher (ORCID: https://orcid.org/0000-0003-1518-2671)
- Hoda Abdelgawad (ORCID: https://orcid.org/0000-0001-6921-6000)
- T. Cooke (ORCID: https://orcid.org/0009-0008-8850-9560)
- Sayed Al‐Aidarous (ORCID: https://orcid.org/0000-0002-7044-9423)
- Kim Rajappan (ORCID: https://orcid.org/0000-0001-8996-2983)
- Arsalan Khalil (ORCID: https://orcid.org/0000-0002-7734-7323)
- Richard Ang (ORCID: https://orcid.org/0000-0002-0385-2124)
- Caroline H. Roney (ORCID: https://orcid.org/0000-0001-6809-0928)
- Sadia Rasheed (ORCID: https://orcid.org/0000-0001-8497-8185)
- Richard Balasubramaniam
- Kayla Chiew (ORCID: https://orcid.org/0000-0002-9694-2494)
- Shohreh Honarbakhsh (ORCID: https://orcid.org/0000-0003-0081-5739)
- Zhen Hua (ORCID: https://orcid.org/0000-0003-1638-2974)
- Lauren Stanton
- Dimitrios Palaiologos
- Syed Ahsan (ORCID: https://orcid.org/0000-0001-9545-9903)
- Νικόλαος Παπαγεωργίου (ORCID: https://orcid.org/0000-0002-2063-2510)
- Saffron Rajappan
- Caterina Vidal Horrach
- Ross J. Hunter (ORCID: https://orcid.org/0000-0002-4641-3279)
- Anthony W. Chow (ORCID: https://orcid.org/0000-0002-8416-3741)
- Suria Geran
- Christopher Primus
- S.M. Afzal Sohaib
- Shahana Hussain
- Meher Lehri
- Sofiane Kouadria
- Gurkiran Sandhar
Institutions
- St Bartholomew's Hospital (GB)
- Queen Mary University of London (GB)
- Royal Bournemouth Hospital (GB)
- Lister Hospital (GB)
- Royal Berkshire Hospital (GB)
- King George Hospital (GB)
- Homerton University Hospital (GB)
- Lung Institute (US)
- Queen's Hospital (GB)
- Oxford University Hospitals NHS Trust (GB)
- Dorset County Hospital (GB)
- North Middlesex Hospital (GB)
- Imperial College London (GB)
Publication Details
- Journal
- Heart Rhythm
- Published
- 2025-11-27
- DOI
- https://doi.org/10.1016/j.hrthm.2025.11.039
- Primary Topic
- Atrial Fibrillation Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.00