High levels of transmitted drug resistance to INSTIs and NNRTIs in Chile: A nationwide prevalence study
TDR prevalence in Chile has increased and main affected families are first-generation INSTIs and NNRTIs. This result highlights the relevance of initiating ART with second-generation INSTIs or PIs, or incorporating baseline genotyping studies when initiating ART with NNRTIs or first-generation INSTIs.
Authors
- Carlos Palma
- María Elena Ceballos (ORCID: https://orcid.org/0000-0002-5569-6485)
- Alejandro Afani
- Olga López
- N. Rodríguez (ORCID: https://orcid.org/0000-0002-5381-6340)
- María Elvira Balcells (ORCID: https://orcid.org/0000-0002-7223-9665)
- Luis Rojas (ORCID: https://orcid.org/0000-0002-0234-5876)
- Marcela Ferrés (ORCID: https://orcid.org/0000-0001-9415-4657)
- Angélica Domínguez de Landa
- Carlos Gallo (ORCID: https://orcid.org/0000-0003-3270-8786)
- Manuel Espinoza (ORCID: https://orcid.org/0000-0001-9564-9512)
- Martín Lasso
- Cinthya Ruiz-Tagle (ORCID: https://orcid.org/0000-0002-4712-3302)
- Michel Serri
- Francisco Salvador Sagüez (ORCID: https://orcid.org/0000-0003-4764-7752)
- Yoselyn M. Castillo
- Felipe Castañeda (ORCID: https://orcid.org/0000-0001-9954-5446)
- Elizabeth Barthel
- Francisco Zamora
- Elisabeth Daube
Institutions
- Universidad de Antofagasta (CL)
- Pontificia Universidad Católica de Chile (CL)
- Hospital Barros Luco-Trudeau (CL)
- Hospital Carlos Van Buren (CL)
- Hospital Regional de Antofagasta (CL)
- Hospital Regional de Concepción (CL)
- Hospital San Juan de Dios (CL)
- Hospital Clínico de la Universidad de Chile (CL)
- Complejo Asistencial Sótero del Río (CL)
- Hospital Regional de Arica Doctor Juan Noé Crevani (CL)
- Hospital del Niño (PA)
- Universidad de Los Lagos (CL)
- Hospital Las Higueras (CL)
Publication Details
- Journal
- Journal of Clinical Virology
- Published
- 2025-11-25
- DOI
- https://doi.org/10.1016/j.jcv.2025.105890
- Primary Topic
- Drug-Induced Adverse Reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00