Sub-chronic exposure to crude acetylene results in the development of deleterious cardio metabolic changes in Sprague Dawley rats
Sub-chronic inhalation of crude acetylene induced metabolic dysfunction characterized by impaired glucose regulation, hepatic steatosis, and oxidative stress, despite no changes in overall body weight. These findings highlight the potential health risks associated with acetylene exposure and underscore the need for regulatory measures to limit its use in fruit ripening.
Authors
- Boniface M. Chege (ORCID: https://orcid.org/0000-0001-8892-3552)
- Charles Githua Githinji
- Peter Waweru (ORCID: https://orcid.org/0000-0003-4232-7952)
- Fred Bukachi
- Caroline Gatwiri Gitonga (ORCID: https://orcid.org/0009-0007-4588-5278)
Institutions
- University of Nairobi (KE)
- Dedan Kimathi University of Technology (KE)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-11-26
- DOI
- https://doi.org/10.1371/journal.pone.0337172
- Primary Topic
- Carcinogens and Genotoxicity Assessment
- Type
- article
- Field-Weighted Citation Impact
- 0.00