Sub-chronic exposure to crude acetylene results in the development of deleterious cardio metabolic changes in Sprague Dawley rats

Sub-chronic inhalation of crude acetylene induced metabolic dysfunction characterized by impaired glucose regulation, hepatic steatosis, and oxidative stress, despite no changes in overall body weight. These findings highlight the potential health risks associated with acetylene exposure and underscore the need for regulatory measures to limit its use in fruit ripening.

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Publication Details

Journal
PLoS ONE
Published
2025-11-26
DOI
https://doi.org/10.1371/journal.pone.0337172
Primary Topic
Carcinogens and Genotoxicity Assessment
Type
article
Field-Weighted Citation Impact
0.00
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article

Sub-chronic exposure to crude acetylene results in the development of deleterious cardio metabolic changes in Sprague Dawley rats

Boniface M. Chege, Charles Githua Githinji, Peter Waweru, Fred Bukachi et al.
PLoS ONE
Carcinogens and Genotoxicity Assessment
article

Sub-chronic exposure to crude acetylene results in the development of deleterious cardio metabolic changes in Sprague Dawley rats

Boniface M. Chege, Charles Githua Githinji, Peter Waweru, Fred Bukachi, Caroline Gatwiri Gitonga
article en

Abstract

Sub-chronic inhalation of crude acetylene induced metabolic dysfunction characterized by impaired glucose regulation, hepatic steatosis, and oxidative stress, despite no changes in overall body weight. These findings highlight the potential health risks associated with acetylene exposure and underscore the need for regulatory measures to limit its use in fruit ripening.

PLoS ONEVol. 20(11)
University of Nairobi (KE), Dedan Kimathi University of Technology (KE)
Openalex Percentile: Top 55%
Carcinogens and Genotoxicity Assessment
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