Reaching the target: time and dose required to achieve target vancomycin plasma concentrations in admitted patients
According to current guidelines, there is no significant difference in the time required to achieve vancomycin target concentrations between neutropenic patients, ARC patients and all vancomycin patients. However, patients weighing >100 kg took nearly a day longer to reach target concentrations (P < 0.001) and required higher maintenance doses, as did neutropenic and ARC patients.
Authors
- Elise J. Smolders (ORCID: https://orcid.org/0000-0001-5694-9758)
- Karin H. M. Larmené‐Beld (ORCID: https://orcid.org/0000-0002-3089-7539)
- Julian D. Machiels (ORCID: https://orcid.org/0000-0003-2606-8276)
- G J Veen
- W. Töpfer
Institutions
- University of Groningen (NL)
- Isala (NL)
Publication Details
- Journal
- Journal of Antimicrobial Chemotherapy
- Published
- 2025-11-26
- DOI
- https://doi.org/10.1093/jac/dkaf424
- Primary Topic
- Antimicrobial Resistance in Staphylococcus
- Type
- article
- Field-Weighted Citation Impact
- 0.00