Integrative Chinese-western therapy for Leukocytoclastic vasculitis-induced refractory leg ulcer: An 8-month healing journey with reduced corticosteroid dependency
This case demonstrates that a combination of oral Chinese herbal decoction and low-dose corticosteroids is a highly effective treatment for recalcitrant wounds caused by LCV, with a low recurrence rate. This approach may contribute to a reduction in corticosteroid or immunosuppressant dosage, promote skin ulcer healing, and reduce recurrence rates. The necessity for future randomized controlled trials is evident to ascertain the efficacy of this therapeutic strategy.
Authors
- Yuan Zong (ORCID: https://orcid.org/0000-0003-1592-732X)
- Yemin Cao (ORCID: https://orcid.org/0000-0002-6617-8501)
- Yongkang Zhang
- Yuzhen Wang (ORCID: https://orcid.org/0000-0002-7544-7937)
- Zhiguo Zhao (ORCID: https://orcid.org/0000-0002-9033-7410)
- Hui Du
Institutions
- Shanghai University of Traditional Chinese Medicine (CN)
- Shanghai First People's Hospital (CN)
Publication Details
- Journal
- EXPLORE
- Published
- 2025-11-26
- DOI
- https://doi.org/10.1016/j.explore.2025.103291
- Primary Topic
- Vasculitis and related conditions
- Type
- article
- Field-Weighted Citation Impact
- 0.00