Skin barrier function in children with eosinophilic esophagitis
Subjects with EoE did not have marked skin barrier dysfunction relative to the controls without EoE and TEWL did not vary according to disease activity. These findings suggest that the utility of TEWL as a biomarker of EoE is limited. Larger studies with defined atopic and nonatopic controls are needed to detect small to moderate differences in skin barrier function.
Authors
- C. Wells (ORCID: https://orcid.org/0000-0002-2850-8805)
- Alfred D. Doyle (ORCID: https://orcid.org/0000-0001-9909-0445)
- Kory Johnson (ORCID: https://orcid.org/0000-0001-7678-3812)
- Blake Civello (ORCID: https://orcid.org/0000-0002-1503-6028)
- Robert Crawford (ORCID: https://orcid.org/0000-0003-2404-641X)
- Shauna R. Schroeder (ORCID: https://orcid.org/0000-0002-7028-354X)
- Benjamin L. Wright (ORCID: https://orcid.org/0000-0002-7586-4722)
- Cindy S. Bauer (ORCID: https://orcid.org/0000-0002-4513-4577)
- Melissa Pecak
Institutions
- University of Arizona (US)
- WinnMed (US)
- Phoenix Children's Hospital (US)
- Mayo Clinic in Arizona (US)
Publication Details
- Journal
- Journal of Allergy and Clinical Immunology Global
- Published
- 2025-11-26
- DOI
- https://doi.org/10.1016/j.jacig.2025.100617
- Primary Topic
- Eosinophilic Esophagitis
- Type
- article
- Field-Weighted Citation Impact
- 0.00