Robotic Cell Micromanipulation Skill Learning via Imitation‐Enhanced Reinforcement Learning

ABSTRACT Humans can learn complex and dexterous manipulation tasks by observing videos, imitating and exploring. Multiple end‐effectors manipulation of free micron‐sized deformable cells is one of the challenging tasks in robotic micromanipulation. We propose an imitation‐enhanced reinforcement learning method inspired by the human learning process that enables robots to learn cell micromanipulation skills from videos. Firstly, for the microscopic robot micromanipulation videos, a multi‐task observation (MTO) network is designed to identify the two end‐effectors and the manipulated objects to obtain the spatiotemporal trajectories. The spatiotemporal constraints of the robot's actions are obtained by the task‐parameterised hidden Markov model (THMM). To simultaneously address the safety and dexterity of robot micromanipulation, an imitation learning optimisation‐based soft actor‐critic (ILOSAC) algorithm is proposed in which the robot can perform skill learning by demonstration and exploration. The proposed method is capable of performing complex cell manipulation tasks in a realistic physical environment. Experiments indicated that compared with current methods and manual remote manipulation, the proposed framework achieved a shorter operation time and less deformation of cells, which is expected to facilitate the development of robot skill learning.

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Publication Details

Journal
CAAI Transactions on Intelligence Technology
Published
2025-11-26
DOI
https://doi.org/10.1049/cit2.70076
Citations
1
Primary Topic
Piezoelectric Actuators and Control
Type
article
Field-Weighted Citation Impact
1.21

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Robotic Cell Micromanipulation Skill Learning via Imitation‐Enhanced Reinforcement Learning

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article

Robotic Cell Micromanipulation Skill Learning via Imitation‐Enhanced Reinforcement Learning

Yibin Ying, Zhongliang Jiang, Youchao Zhang, Mingchuan Zhou, Alois Knoll, Xiangyu Guo, Fanghao Wang
article en
1 citations

Abstract

ABSTRACT Humans can learn complex and dexterous manipulation tasks by observing videos, imitating and exploring. Multiple end‐effectors manipulation of free micron‐sized deformable cells is one of the challenging tasks in robotic micromanipulation. We propose an imitation‐enhanced reinforcement learning method inspired by the human learning process that enables robots to learn cell micromanipulation skills from videos. Firstly, for the microscopic robot micromanipulation videos, a multi‐task observation (MTO) network is designed to identify the two end‐effectors and the manipulated objects to obtain the spatiotemporal trajectories. The spatiotemporal constraints of the robot's actions are obtained by the task‐parameterised hidden Markov model (THMM). To simultaneously address the safety and dexterity of robot micromanipulation, an imitation learning optimisation‐based soft actor‐critic (ILOSAC) algorithm is proposed in which the robot can perform skill learning by demonstration and exploration. The proposed method is capable of performing complex cell manipulation tasks in a realistic physical environment. Experiments indicated that compared with current methods and manual remote manipulation, the proposed framework achieved a shorter operation time and less deformation of cells, which is expected to facilitate the development of robot skill learning.

CAAI Transactions on Intelligence TechnologyVol. 11(1)
Innovation Team (China) (HK), Technical University of Munich (DE), Zhejiang University (CN), University of Hong Kong (HK)
National Natural Science Foundation of China
Openalex Percentile: Top 15%
Piezoelectric Actuators and Control
1.21
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