Stigmasterol exerts antioxidant effects through activation of the Keap1/Nrf2 signaling pathway in Parkinson’s disease model
Our results indicate that ST has an antioxidant role in the PD model through activating the Keap1/Nrf2 signaling pathway, offering a theoretical foundation for its potential therapeutic use in PD treatment.
Authors
- Shaogang Qu (ORCID: https://orcid.org/0000-0002-0647-3701)
- Ren‐He Xu (ORCID: https://orcid.org/0000-0002-3410-3353)
- Qi Luo (ORCID: https://orcid.org/0000-0001-8163-8935)
- Zhiting Wan
- Yigang Tong (ORCID: https://orcid.org/0000-0002-8503-8045)
- Qi Qu (ORCID: https://orcid.org/0000-0002-4870-6606)
Institutions
- University of Macau (MO)
- Ganzhou People's Hospital (CN)
- Nanfang Hospital (CN)
- Shanghai Center for Brain Science and Brain-Inspired Technology (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-11-26
- DOI
- https://doi.org/10.1186/s12967-025-07502-2
- Primary Topic
- Genomics, phytochemicals, and oxidative stress
- Type
- article
- Field-Weighted Citation Impact
- 0.00