Cell State Transitions Drive the Evolution of Disease Progression in B-Lymphoblastic Leukemia
Flow cytometry characterization of B-ALL samples (diagnosis, remission, and relapse) is used to parameterize a mathematical model of cell state transition rates and stratify patients for post-induction chemotherapy MRD.
Authors
- Curtis Gravenmier (ORCID: https://orcid.org/0000-0003-4120-5339)
- Bijal Shah (ORCID: https://orcid.org/0000-0003-4328-6021)
- Yi-Han Tang (ORCID: https://orcid.org/0009-0006-2248-1978)
- Sadegh Marzban (ORCID: https://orcid.org/0000-0002-9435-017X)
- Jeffrey West (ORCID: https://orcid.org/0000-0001-9579-4664)
- Nancy Gillis (ORCID: https://orcid.org/0000-0002-7744-8490)
- Ling Zhang (ORCID: https://orcid.org/0000-0002-1463-1458)
- Lynn C. Moscinski (ORCID: https://orcid.org/0000-0002-2609-4063)
Institutions
- Moffitt Cancer Center (US)
Publication Details
- Journal
- Cancer Research Communications
- Published
- 2025-11-26
- DOI
- https://doi.org/10.1158/2767-9764.crc-25-0277
- Citations
- 1
- Primary Topic
- Acute Lymphoblastic Leukemia research
- Type
- article
- Field-Weighted Citation Impact
- 1.88
Funders
- University of South Florida
- Moffitt Cancer Center