Pancreatic involvement and its prognostic impact in acute-on-chronic liver failure
Increased lipase and (alpha-)amylase levels are common in ACLF. Notably, lipase levels ≥3x ULN at ACLF-D7 predict mortality independent from liver function, suggesting a role in disease progression.
Authors
- Nina Dominik (ORCID: https://orcid.org/0009-0009-4615-915X)
- Paul Thöne (ORCID: https://orcid.org/0009-0001-1618-476X)
- Benedikt Simbrunner (ORCID: https://orcid.org/0000-0001-8181-9146)
- Lukas Hartl (ORCID: https://orcid.org/0000-0003-3398-6120)
- Vlad Țâru (ORCID: https://orcid.org/0000-0002-2313-7881)
- Georg Semmler (ORCID: https://orcid.org/0000-0002-0411-166X)
- Mattias Mandorfer (ORCID: https://orcid.org/0000-0003-2330-0017)
- Mathias Schneeweiss‐Gleixner (ORCID: https://orcid.org/0009-0001-5296-1212)
- Thomas Reiberger (ORCID: https://orcid.org/0000-0002-4590-3583)
- M Hintersteininger
- Benedikt Silvester Hofer (ORCID: https://orcid.org/0000-0003-3403-3372)
- Mathias Jachs (ORCID: https://orcid.org/0000-0003-2871-4147)
- Michael A Trauner (ORCID: https://orcid.org/0000-0002-1275-6425)
- Lorenz Balcar (ORCID: https://orcid.org/0000-0002-6708-3061)
- Philipp Schwabl
- Georg Kramer (ORCID: https://orcid.org/0009-0008-1736-3699)
- Christian Sebesta (ORCID: https://orcid.org/0009-0001-7504-8506)
Institutions
- Medical University of Vienna (AT)
Publication Details
- Journal
- Annals of Hepatology
- Published
- 2025-11-26
- DOI
- https://doi.org/10.1016/j.aohep.2025.102165
- Primary Topic
- Pancreatitis Pathology and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00